The Cadasil Consortium sends all wet biomarker samples to NCRAD 


The goal of the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) is to support research focused on the etiology, early detection and therapeutic development for Alzheimer disease and related dementias. To accomplish this goal, in 1990, NCRAD was funded by the National Institutes on Aging (NIA). NCRAD is a national resource where clinical information and biological materials, such as DNA, plasma, serum, RNA, CSF, cell lines and brain tissue can be stored and requested. NCRAD currently maintains samples from individuals with Alzheimer’s disease and/or related dementias as well as healthy controls.


For more than 30 years, NCRAD has been a key research infrastructure for NIA to support ADRD research. NCRAD’s mission has grown from a DNA storage repository for genetic studies to a specialized research repository that supports a broad range of biospecimens and focuses on the aspects of sample collection, storage, distribution, and processing. NCRAD’s success is driven by the use of standard operating procedures to ensure uniformity and to minimizing the impact of preanalytical variables on downstream sample analyses.