(CADASIL) Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy is the most common vascular dementia. Individuals with CADASIL are destined to develop vascular cognitive impairment and dementia (VCID) which greatly impacts their quality of life.   

Our research team is dedicated to finding ways to intervene in the CADASIL trajectory by using a more common form of dementia (autosomal dominant vascular) as a model to investigate specific features of VCID and to study interactions with risk factors impacting the aging life course.